Short answer: absolutely. I've done it, and I've watched other business owners do it.
Lenders set origination fees with margin built in. They expect some borrowers to push back. Here's what actually works:
Come with competing offers. Nothing moves a lender faster than knowing you're shopping. Get term sheets from at least three lenders and let each one know you're comparing. I've seen origination fees drop from 3% to 1% just by showing a competitor's offer letter.
Offer something in return. Lenders are more willing to cut fees if you'll set up automatic payments, maintain a business deposit account with them, or accept a slightly higher interest rate. It's a trade, not a demand.
Ask about fee waivers for strong applications. If your business has two-plus years of profitable history, strong personal credit above 720, and you're borrowing a substantial amount, you have leverage. The lender wants your business.
Time it right. End of quarter, end of year — loan officers have quotas. They're more flexible on fees when they need to close deals.
What doesn't work: demanding lower fees with no leverage, being adversarial, or trying to negotiate after you've already signed the commitment letter. The time to negotiate is after you receive the term sheet but before you sign anything binding.
One more thing — online lenders typically have less fee flexibility than banks and credit unions because their pricing is algorithm-driven. If negotiation matters to you, relationship lenders are usually your better bet.